Let's hope no one was suggesting putting transfusion on gameboy advance... seriously. Duke Nukem couldn't even be recreated on that system. 3D Realms was lucky to pully off a "GBA Exclusive" Version.
besides... FPS's suck on GBAs. More than anything else.
Well, if you have 1.5 firmware. If you have above 1.5, you're screwed as far as homebrew. I mainly use mine for homebrew. All I play is Lumines as far as UMDs, and I spend the rest of my time playing Doom and a slew of NES games. They have Quake as well, and I think they have Duke somewhere out there.